CBD wholesalers should “have big concerns” about the U.S. Food and Drug Administration’s growing unease about the safety of the cannabis compound, according to one chief executive officer.

The FDA said Monday that it “cannot conclude that CBD is generally recognized as safe among qualified experts for its use in human or animal food.”

It added that “some of the available data raise serious concerns about potential harm from CBD,” including liver injury, drowsiness, diarrhea and changes in mood, and raised questions about its impact on children and pregnant or breastfeeding women.

This could cause big retailers to shy away from products containing cannabidiol, a non-intoxicating compound found in the cannabis plant, said Peter Horvath, CEO of Green Growth Brands Inc.

“It could be that this FDA thing causes the chains to either cut back or discontinue their CBD businesses,” Horvath said in a phone interview Tuesday. “I think if you’re in a strictly wholesale strategy…

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